
Some lizards possess an astonishing ability that allows them to regenerate parts of their bodies, particularly their tails. This process, known as autotomy, helps them escape predators by sacrificing a body part that continues to move after detachment. The predator is distracted by the twitching piece, giving the animal a chance to flee to safety.
Once the danger has passed, the regeneration process begins. Specialized cells at the wound site start dividing rapidly to form new tissues. Over time, cartilage, muscles, and skin rebuild the missing section, though the new part may differ slightly in texture or color from the original. This biological repair system is one of nature’s most impressive survival mechanisms.
The regrowth is not just about replacing what was lost—it also demonstrates the complexity of their physiology. The ability to heal without severe infection or permanent damage showcases their advanced natural defenses. Scientists continue to study this process to better understand how it might be applied to human medicine, particularly in tissue regeneration and wound healing.
During the regeneration phase, these creatures tend to conserve energy by reducing activity. They often seek shelter and avoid unnecessary movement to allow the body to focus on healing. Nutrition also plays a vital role, as protein and minerals support tissue growth and recovery.
This remarkable adaptation is not without its limits. While tails can grow back, other limbs or body parts may not fully regenerate in the same way. Still, this ability provides a major advantage in the wild, where threats are constant and quick recovery can mean the difference between survival and death.

Lizards that Can Regrow Limbs
Green Anole (Anolis carolinensis)
This common North American lizard is a model organism in regeneration research. It can completely regenerate its tail, including the spinal cord, cartilage, and muscle. While it cannot regrow a full limb, studies on its tail regeneration are crucial for understanding the potential for more complex tissue regeneration.
Leopard Gecko (Eublepharis macularius)
A classic example of tail autonomy and regeneration. Leopard geckos store fat in their tails and can voluntarily drop them to escape predators. The regenerated tail is often different in color, texture, and structure—typically made of cartilage rather than bone—but is fully functional.
Crested Gecko (Correlophus ciliatus)
Unlike many lizards, crested geckos cannot regenerate their tails once lost. They are included here as a notable exception that highlights the diversity within lizard biology. A tailless crested gecko is perfectly healthy but is known as a “frogbutt” in the pet trade.
Western Fence Lizard (Sceloporus occidentalis)
This widespread North American lizard is highly proficient at tail regeneration. The regrown tail serves its purpose for balance and fat storage, though, like in most species, the new tail is not a perfect anatomical replica of the original.
Common House Gecko (Hemidactylus frenatus)
This widespread tropical gecko is an expert at tail loss and regeneration. Its tail wriggles vigorously after being detached, creating a effective distraction that allows the gecko to escape. The regeneration process is rapid and efficient.
Italian Wall Lizard (Podarcis sicula)
A highly adaptable species that has been the subject of evolutionary studies. Like most lizards in its family (Lacertidae), it can readily autotomize and regenerate its tail, which is a key survival tactic in its predator-rich environments.
Gila Monster (Heloderma suspectum)
One of the few venomous lizards, the Gila Monster has limited regenerative abilities compared to smaller lizards. It can regenerate its tail, but the process is slower, and the new tail is often noticeably shorter and blunter than the original.
Blue-Tongued Skink (Tiliqua spp.)
These large, stout skinks can regenerate their tails if they are dropped. However, their tails do not autotomize as easily as those of other lizards, and the regrown tail is typically a short, dark, and stubby version of the original.
Mexican Alligator Lizard (Abronia graminea)
This arboreal lizard can regenerate its long, prehensile tail. Given its life in the trees, a functional tail is crucial for balance, making this ability vital for its survival. The regrown tail is often a different shade of green.
Five-Lined Skink (Plestiodon fasciatus)
This common North American skink is famous for the bright blue tail of its juveniles. This vibrant coloration may draw a predator’s attack to the detachable tail rather than the body. They are highly proficient at regenerating a new, fully functional tail after autotomy.
Giant Day Gecko (Phelsuma grandis)
Unlike its relative, the crested gecko, the Giant Day Gecko can regenerate its tail if it is lost. The process is efficient, and the new tail, while often a slightly different shade of green, allows the gecko to maintain its excellent balance while climbing smooth surfaces.
Savannah Monitor (Varanus exanthematicus)
While large monitors like the Savannah Monitor have a more limited capacity for regeneration compared to smaller lizards, they can heal severe tail injuries and regrow lost portions of the tail tip. The regenerated section is typically shorter and lacks the original scale pattern.
Ocellated Skink (Chalcides ocellatus)
This skink, with its snake-like body and small limbs, relies heavily on its tail for movement and stored energy. It can autotomize its tail and will regenerate a new one, though the replacement is often shorter and differently colored than the original.
Sandfish Skink (Scincus scincus)
Known for “swimming” through desert sand, the Sandfish Skink can shed its tail to escape a predator’s grasp. It will subsequently regenerate a new tail, which is essential for maintaining its hydrodynamic shape and balance during its unique subsurface locomotion.
Common Wall Gecko (Tarentola mauritanica)
This widespread Mediterranean gecko can easily detach its tail when grabbed. The lost tail is regrown over time, but the new version is typically smoother, lacks the pronounced tubercles of the original, and is often a different, more muted color.